SOST: Msg can’t be transferred to node SMTP due to connection error

You have configured the SMTP email setting from transaction code SCOT. You sent an email but in transaction code SOST (from the trace file), below error coming out.

SX_GENERATE_NDR	G	Message cannot be transferred to node SMTP 
                        due to connection error (final)

Solution

1. Check below articles and confirm all settings have been correctly configured.

• SOST: Cannot process message, no route from USER to EMAIL

• SOST: Error while automatically determining the default internet domain

• SOST: Wait for communications service

2. Next, test the connection and authentication from your local computer to the mail server using the telnet.

telnet IP-ADDRESS PORT

You should get the message something like below, and type helo to check and ensure your SAP system IP address is authenticated with the mail server. If you are getting error message, you need to include your SAP system IP address into the mail server authentication.

220 ARAMAILSERVER.com Microsoft ESMTP MAIL Service ready at Sun, 24 Nov 201
3 12:25:05 +0800
helo
250 ARAMAILSERVER.com Hello [192.168.0.100]

Reference

SAP Note 487754